In my opinion, yes, if you follow these guidelines:
That said, you should try to connect your question with Ethereum. For example, a question solely about some parameter in the Truebit paper is likely to be off-topic.
The guidelines above also include:
If you ask a vague question, you’ll get a vague answer. But if you
give us details and context, we can provide a useful answer.
Make it relevant to others
We like to help as many people at a time as we can. Make it clear how
your question is relevant to more people than just you, and more of us
will be interested in your question and willing to look into it.
As Truebit is highly in the idea stage, it may be difficult to find a specific question that's relevant to others and has a reasonably fixed answer that minimizes speculation on what Truebit and Ethereum will be in the future.
If you're in doubt, try posting some of your top questions first and see how the community votes on it.